Urea helps your skin retain moisture to keep it hydrated. Lauromacrogols act as a topical anaesthetic for your skin, helping to relieve the itch. Treats and soothes the itching caused by eczema, dermatitis, pruritus and scaling skin conditions. Formulated with urea, a moisturiser found naturally within the skin, E45 Itch Relief Cream is non-greasy, moisturising and can soothe the skin and leave it feeling calm and comfortable. Perfume-free – dermatologically tested.