NR (Nicotinamide Riboside) is a form of vitamin B3 that is used to boost levels of NAD+ in the body, which is important for cellular energy and repair. Astaxanthin is a potent antioxidant. When taking NR with Astaxanthin, individuals should be cautious if they have liver issues as high doses of NR may affect liver function. Furthermore, as Astaxanthin is a potent antioxidant, it may interact with certain medications, and people on anticoagulants should exercise caution. Pregnant or breastfeeding women, and individuals with known medical conditions or taking medication, should consult a healthcare professional before taking supplements.