Vitamin B12 is generally considered safe for most people when taken in appropriate amounts. However, high doses of B12 might cause mild side effects such as rashes, itching, or diarrhoea. People with allergies or sensitivities to cobalt or cobalamin should avoid B12 supplements. Individuals with Leber's disease should not take vitamin B12 as it could harm the optic nerve. It's also important to be cautious when taking B12 supplements alongside certain medications, such as metformin or stomach acid reducers, as there might be interactions. Consulting a healthcare professional before beginning supplementation, especially if you have underlying health conditions, is recommended.

Keep out of reach of children and do not consume if pregnant or breastfeeding.

Food supplements should not be used as a substitute to a healthy diet and lifestyle.