DO NOT use Ovesse if you:

Are allergic to estriol or any of the other ingredients

Have or ever had womb or ovarian cancer

Have or recently had vaginal or genital bleeding, since your periods stopped due to the menopause

Have recent of suspected endometrial hyperplasia (or e.g. you have been referred for an ultrasound or your womb and are awaiting results)

Have previously been treated with oestrogen only systemic HRT (without Progestogen) and you have not had your womb removed

Have any thickening, lump or scarring on your vulva

Have severe vaginal itching, or itchy patches or rash on your vulva

Have a current vaginal infection prior to starting treatment

Have or ever had breast cancer, or have a lump / change in appearance in your breast, or nipple discharge

Have or ever had a blood clot in a vein

Have or ever had a heart attack, stroke or angina

Have blood clotting disorder

Have liver disease and your liver function tests have not returned to normal

Have a rare condition called 'porphyria'


Certain conditions may be made worse during oestrogen treatment, see section 2 of the package leaflet for more information.