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About Osentia

Osentia® is the first clinically proven, safe and accurate at-home test that can help identify your individual risk of fragility fractures, a common sign of osteoporosis.

Did you know that our bones start to age as we enter our mid-thirties? As a result by the age of 50, one in two women and one in five men will suffer a fracture due to fragile bones.1

Fragile bones are a common sign that you may have osteoporosis. It’s a condition in which your bones lose their strength and are more likely to break following a minor bump or fall. These breaks are known as fragility fractures.

Everyone has some risk of developing osteoporosis, which is often undiagnosed until the time you fracture a bone. It is therefore important to identify the risk of osteoporosis early enough to take steps to help prevent and minimise the development of the condition and reduce the risk of fracture.

What does the Osentia® test contain?

The kit contains:

  • Instructions for use
  • Questionnaire order form
  • A collection bag for the nail sample
  • An envelope for the nail clipping and a pre-paid envelope to post the order form and sample collection bag back to the laboratory for analysis

How does Osentia® work?

The unique test only needs a fingernail or toenail clipping, measuring 2mm or more in depth and 5mm, which is then sent via post, in the prepaid envelope, to Osentia's® laboratory for analysis using the latest screening technology.

You also need to complete a test order form which includes questions about your health and lifestyle. The test will accurately provide your personal risk of a fragility fracture, which is an early indicator of your risk of developing osteoporosis.

The result will be returned to you via email or post within seven days.

References

1. National Osteoporosis Society. All about osteoporosis and bone health [online] 2015. Available from https://www.nos.org.uk/~/document.doc?id=1848 [Last accessed September 2016]

Like a fingerprint your nail is unique. Osentia® looks for changes in the nail structure, which correlate with your risk of developing osteoporosis, providing you with a personalised result.

Your result is based on the personal information you provide and the laboratory analysis of your fingernail or toenail clipping. You will receive personalised advice on how to reduce your risk of developing a fragility fracture, through simple diet and lifestyle changes.

Understanding your results

So you can understand your results better, Osentia® has separated risk into three different types of profile, or ‘traffic lights’. Using this traffic light system alongside further detailed results, it can provide tailored recommendations to help you minimise your risk of fragility fractures.

  • This means you currently have a lower than average risk of suffering from fragility fractures

  • This means you currently have a moderate risk of suffering from fragility fractures

  • This means you currently have a relatively high risk of suffering from fragility fractures

Everyone who completes the Osentia® test will be sent a tailored risk profile and a copy of Understanding and Managing Osteoporosis Risk Factors, a booklet packed with health and lifestyle information to help manage and minimise the risk of developing osteoporosis.

The results will be returned to you via email or post within seven days.

  • What are fragility fractures?

    A fragility fracture is a fall from a standing height or less, that results in a fracture. Bones are living tissue, which continue to remodel, reaching peak bone mass in a person in their late 20s. However, as people age, bones start to lose their strength and density making them more susceptible to fractures.

What is osteoporosis?

Osteoporosis is a condition that weakens the bones making them fragile and more likely to break. It is commonly known as the ‘silent disease’ as it can remain undiagnosed until a bone is fractured.1

Broken bones or ‘fragility fractures’ caused by osteoporosis can affect various parts of the body; the wrists, hips and spine are the most commonly affected sites.2

Unfortunately, people who have had one fracture are at greater risk of another – around 23% of secondary fractures occur within a year of the initial fracture. Fragility fractures caused by osteoporosis can have a devastating effect on the day-to-day lives of sufferers, affecting mobility and resulting in a loss of independence. 3
 

Risk factors for osteoporosis

Osteoporosis is more common in women than in men. This is because hormone changes that occur through the menopause directly affect bone density.4 Age is also a major risk factor for osteoporosis; our bones start to age as we enter our mid-thirties and as a result, one in two women and one in five men over the age of 50 will suffer a fracture due to weakened bones.2

    As well as age, many other factors can determine your risk of suffering from a fragility fracture:

  • Family members with osteoporosis may have an increased chance of developing this condition
  • Poor diet, lack of exercise, smoking, excessive alcohol consumption and eating disorders may increase risk
  • Medical conditions such as rheumatoid arthritis, coeliac disease and hyperthyroidism can also have an effect
  • Treatments such as glucocorticoid steroids, certain breast or prostate cancer therapies and anti-epileptic drugs
  • Menopause can also increase your risk

References

1. National Osteoporosis Society. What is Osteoporosis? Available from: https://www.nos.org.uk/about-osteoporosis

2. Call to Action. HCPs: Are you confident that your patients at risk of fracture are being identified and receiving appropriate care? Osteoporosis in the UK….Breaking Point. Available from: http://www.thebms.org.uk/publicdownloads/Call_to_Action_HCP.PDF [Last accessed: May 2016]

2. National Osteoporosis Society. All about osteoporosis and bone health. Available from: https://www.nos.org.uk/~/document.doc?id=1848

3. National Osteoporosis Society. Effective Secondary prevention of Fragility Fractures. Clinical Standards for Fracture Liaison Services. April 2015. Available from: https://www.nos.org.uk/document.doc?id=1941

4. NHS Choices. Osteoporosis-Causes. Available from: http://www.nhs.uk/Conditions/Osteoporosis/Pages/Causes.aspx

  • Visit the National Osteoporosis Society for more information and support about osteoporosis and bone health at www.nos.org.uk
  • NHS Choices, the UK’s biggest health website, provides a detailed overview of the causes, prevention and diagnosis of osteoporosis Visit www.nhs.uk/Conditions/Osteoporosis/Pages/Introduction.aspx